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Does injection of single dose of dexmedetomidine improves the quality and duration of spinal anaesthesia

Effect of single intravenous bolus dose of dexmedetomidine on block charecteristics of spinal anaesthesia with hyperbaric bupivacaine - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109349
Enrollment
100
Registered
2026-04-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: intravenous dexmedetomidine: we will give the single intravenous bolus dose of dexmedetomidine (0.5 mcg/kg) diluted with normal saline to 20ml, 10 min before spinal anaesthesia and asse

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients belonging to ASA physical status I,II patients weighing between 50-80 kgs patient height between 150-180 cms duration of surgery 45-120 min

Exclusion criteria

Exclusion criteria: refuse to participate in the study presence of known allergy to drugs used in the study any contraindication to sub-arachnoid block patients with heart block, bradycardia, conduction abnormalities and on beta blockers inability to understand the use of visual analog scale

Design outcomes

Primary

MeasureTime frame
To study the effect of intravenous dexmedetomidine on duration of sensory blockTimepoint: at 0 min, every 2 min for the first 10 min, every 15 min till the end of surgery

Secondary

MeasureTime frame
to assess the time taken for two dermatomal regression of sensory blockTimepoint: at 0 min, every 2 min for the first 10 min, every 15 min till the complete resolution;to assess total duration of motor block(from grade I till complete resolution)Timepoint: at 0 min, every 2 min for the first 10 min, every 15 min till the end of surgery;to assess total duration of analgesia- using Visual analogue scaleTimepoint: at the end of surgery, every 30 min till VAS is more than 4;to assess intraoperative & postoperative sedation levelTimepoint: at 0 min, every 15 min till end of surgery, every 30 min thereafter;to observe hemodynamic changes & any adverse eventsTimepoint: at baseline, at 0 min, every 5 min for the first 20 min, every 10 min till the end of surgery, every 30 min thereafter

Countries

India

Contacts

Public ContactDr Ashima Vohra

Hindu rao hospital

drashima_1981@rediffmail.com95829111125

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026