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Impact of Giving Paracetamol Before or After Intubation on Shivering and Pain

Comparative study between preintubation and preextubation paracetamol for postoperative shivering and analgesia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109291
Enrollment
60
Registered
2026-04-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H60-H95- Diseases of the ear and mastoid process Health Condition 2: R52- Pain, unspecified

Interventions

Intervention1: Pre-intubation IV Paracetamol: Paracetamol infusion given before intubation. Dose: 15 mg/kg IV. Infused over 10 minutes. Control Intervention1: Pre-extubation IV Paracetamol: Paracetamo

Sponsors

Nehal Patodi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to participate in the study with ASA grade 1 and 2 undergoing elective surgery of 1-4 hours under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patients refusing, patients belonging to ASA grade 3, 4 and 5, patients with allergy to paracetamol, patients having a temperature less than 30 degrees centigrade or greater than 36 degrees centigrade, patients with hypo/hyper thyroidism, diabetes or on medications like CCBs, vasodilators, betablockers, etc.

Design outcomes

Primary

MeasureTime frame
Shivering PainTimepoint: Just after extubation then Hourly till 12 hours—

Secondary

MeasureTime frame
Adverse effects like nausea, vomiting & hypotensionTimepoint: within 12 hours after extubation—

Countries

India

Contacts

Public ContactJigisha Mehta

Sumandeep Vidyapeeth

jbmehta.28@gmail.com8866718168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026