Comparison of EXORA block versus subcostal TAP block for postoperative pain relief after laparoscopic cholecystectomy under general anesthesia.

Efficacy of Ultrasound guided External Oblique and Rectus Abdominis plane block (EXORA) versus Subcostal TAP block on duration of postoperative analgesia in patients undergoing laparoscopic cholecystectomy under General Anesthesia - a double blinded randomized comparative study - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109241

Enrollment

Registered

2026-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 2: K808- Other cholelithiasis

Interventions

Intervention1: EXORA BLOCK: Ultrasound-guided External Oblique and Rectus Abdominis Plane Block performed bilaterally after induction of anesthesia. Control Intervention1: Subcostal TAP Block: Ultraso

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged 18 to 60 years. ASA physical status I to II. Scheduled for elective laparoscopic cholecystectomy. Willing to provide written informed consent.

Exclusion criteria

Exclusion criteria: Patient refusal / not willing to provide written informed consent.ASA grade III to IV.Known allergy to local anesthetics.BMI greater than 35 kg/m .Coagulopathy or use of anticoagulants.Infection at the block site.Chronic opioid use or pre-existing chronic pain disorders.Severe hepatic or renal dysfunction.Pregnant or lactating women

Design outcomes

Primary

Measure	Time frame
Duration of postoperative analgesia / time to first rescue analgesic requirement within 24 hoursTimepoint: No time point	—

Secondary

Measure	Time frame
1.Total opioid/rescue analgesic consumption in the first 48 hours. 2.Hemodynamic changes intraoperative (recorded post induction,post block, and at consequent 30 min intervals.) 3. Intraoperative Fentanyl requirement 4. NRS scores assessed at given time points. 5. QoR 15 questionnaire at 48hr. 6.Adverse effects like sedation, nausea, vomitingTimepoint: 0,2,4,6,8,12,24,48 hr	—

Countries

India

Contacts

Public ContactDr Ananya Padhy

Institute of Medical Sciences and SUM hospital

Dr.shikhaawal@gmail.com09818987670

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026