Health Condition 1: O82- Encounter for cesarean delivery without indication
Conditions
Interventions
Intervention1: PHENYLEPHRINE IN PATIENTS UNDERGOING LOWER SEGMENT CAESAREAN SECTION: A prospective observational study evaluating the effectiveness of phenylephrine, ondansetron, and their combinatio
Sponsors
Gandhi Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria included patients aged 18 35 years, belonging to American Society of Anesthesiologists (ASA) physical status Grade I or II, with a singleton pregnancy, and scheduled for lower segment cesarean section (LSCS) under spinal anesthesia.
Exclusion criteria
Exclusion criteria: Exclusion criteria included patients who refused to participate had contraindications to spinal anesthesia allergy to study drugs history of bleeding disorders or postoperative nausea and vomiting any significant comorbid conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidences of intra operative nausea and vomiting after administrating phenylephrine, ondansetron or combination of both in three different groupsTimepoint: Blinded personnel will record NIBP at 5-minute intervals for 15 minutes post-spinal anesthesia, then every 15 minutes until delivery, and every 5 minutes for 10 minutes post-delivery. Heart rate will be continuously monitored. Nausea will be assessed at 5-minute intervals for 10 minutes, then every 10 minutes until 10 minutes post-delivery, along with vomiting episodes and rescue antiemetic use. Postoperative nausea, vomiting, and antiemetic use will be recorded at 2 and 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess intraoperative hemodynamic stability. To assess incidence of PONV To observe maternal satisfaction with management of nausea and vomiting To assess need for rescue antiemetics and any vasopressor To record any adverse effects Timepoint: non-invasive blood pressure (NIBP) readings every 5 minute for the first 15 minutes following spinal anesthesia, then every 15 minutes until delivery, and every 5 minute for 10 minutes after delivery. Heart rate, intraoperative nausea scores, number of vomiting episodes, and the need for rescue antiemetics will also be recorded. Nausea scores will be elicited from all participants at 5-minute intervals for the first 10 minutes following spinal anesthesia and then at 10-minute intervals until 10 minutes post-delivery. Postoperatively, participants will self-report nausea scores, number of vomiting episodes, and the need for rescue antiemetics during two intervals: from 0 2 hours and from 2 24 hours after surgery (with time 0 defined as the time of operating room exit). | — |
Countries
India
Contacts
Public ContactDr Urmila Keshari
Hamidia hospital Gandhi medical college bhopal
Outcome results
None listed