Health Condition 1: PCS- Health Condition 2: G890- Central pain syndrome
Conditions
Interventions
Intervention1: Intermittent Theta Burst Stimulation: Intermittent TBS (iTBS), which involves TBS training for 2 seconds (3-pulse burst at 50 Hz -20 ms between pulses.) at intervals of 8 seconds for a
Sponsors
Principal Investigator
Eligibility
Inclusion criteria
Inclusion criteria: 1. In this prospective follow up study, we will enroll patients presenting with Central Post Stroke Pain above the age of 18 years presented within 6 months of onset of stroke. 2. Subjects willing to comply to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with major psychiatric (substance abuse, psychotic disorders) or neurological disease (Epilepsy, head injury or tumor), malignancy, liver, or kidney failure. 2. Patients with cardiac diseases, bronchial asthma, bleeding disorders, or pregnancy. 3. Patients with electronic or magnetic implants i.e. pacemaker, intracranial metal objects, or artificial metal tooth in-situ. 4. Patients with ongoing medications that decreases seizure threshold or family history of epilepsy. 5. Those unwilling to give consent will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the efficacy of Theta Burst Stimulation in treatment of Central Post stroke Pain in terms of Change in NRS from baseline to 1 and 3 months.Timepoint: 1 & 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the efficacy of Theta Burst Stimulation in treatment of Central Post stroke Pain in terms of Change in SFMPQ-2 score, HAM-A, HAM-D, and SS-QOL from baseline to 1 and 3 months.Timepoint: 1 & 3 months;Comparison of PGIC scores in both the groups at end of 3months.Timepoint: 3 months;DTI values in Spinothalamic tract and Thalamocortical tract (FA, ADC values) changes from baseline to post 3 -months post TBS.Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactVARUN KUMAR SINGH
Institute of Medical Sciences
Outcome results
None listed