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A study to see if a safe brain stimulation treatment can help people with schizophrenia feel better and more active

EFFICACY OF r TMS IN RESIDUAL NEGATIVE SYMPTOMS IN SCHIZOPHRENIA: A DOUBLE-BLIND PLACEBO CONTROL TRIAL - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109153
Enrollment
35
Registered
2026-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F205- Residual schizophrenia

Interventions

Intervention1: Active repetitive transcranial magnetic stimulation: High frequency repetitive transcranial magnetic stimulation will be delivered over the left dorsolateral prefrontal cortex using a f

Sponsors

Subharti medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 55 years diagnosed with schizophrenia as per ICD 10 criteria. Patients with predominant residual negative symptoms and clinically stable on antipsychotic medication for at least four weeks. Patients with a reliable informant and willing to provide informed consent.

Exclusion criteria

Exclusion criteria: Patients with history of neurological illness, head injury, or seizure disorder. Patients with comorbid depressive episode or on antidepressant treatment in the past four weeks. Patients with implanted metallic or electronic devices such as pacemakers or cochlear implants. Patients with severe medical illness including congestive heart failure or increased intracranial pressure. Pregnant or lactating females. Patients with severe positive symptoms interfering with study participation.

Design outcomes

Primary

MeasureTime frame
Change in severity of residual negative symptoms as measured by PANSS Negative Subscale score.Timepoint: Change in severity of residual negative symptoms as measured by PANSS Negative Subscale score.

Secondary

MeasureTime frame
Change in total PANSS scoreTimepoint: Baseline, 2 weeks, 2 months

Countries

India

Contacts

Public ContactDr Adarsh kasana

subharti medical college and hospital, swami vivekanand subharti unversity, meerut

kasanaadarsh@gmail.com9999841418

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026