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Clinical and Radiographic Healing in Participants Following Exposure to Biodentine and Bio-C Repair for Partial Pulpotomy in Carious Permanent Molars

CLINICAL AND RADIOGRAPHIC OUTCOMES OF PARTIAL PULPOTOMY USING BIODENTINE AND BIO-C REPAIR IN THE MANAGEMENT OF CARIOUS MATURE PERMANENT MOLARS DIAGNOSED WITH SYMPTOMATIC IRREVERSIBLE PULPITIS : A RANDOMISED CONTROLLED TRIAL - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109145
Enrollment
40
Registered
2026-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Mature Permanent Molars with irreversible pulpitis treated by Partial Pulpotomy using Bio-C Repair.: Mature Permanent Molars with irreversible pulpitis treated by partial pulpotomy usi

Sponsors

Dr. Divya Grover
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Non- contributory medical history Patients with clinical presentation of spontaneous pain or pain exacerbated by cold stimuli and lasting for a few seconds to several hours and which could be reproduced using cold testing / EPT. Positive response to cold testing with no signs of pulpal necrosis including swelling or sinus tract. The tooth is restorable with no need for a crown or post-retained restoration. Normal probing pocket depth and tooth mobility. Patients with radiographic evidence of caries involving the entire thickness of dentine. Normal periapical structures.

Exclusion criteria

Exclusion criteria: Immature molars with open apex. Radiolucency at the periapical zones or furcation. Existence of calcification (pulp stone, diffuse calcification, disk-like chamber) and internal or external resorption. Existence of swelling of the sinus tract and the negative response to testing. Uncontrolled bleeding after pulpotomy lasting for more than 10 minutes. Bleeding is not sufficient after pulp exposure; the pulp is judged partially necrotic. Non-restorable teeth.

Design outcomes

Primary

MeasureTime frame
Outcome will be assessed on Clinical Evaluation and Radiographic Assessment.Timepoint: At 1 month and 6 months.

Secondary

MeasureTime frame
Outcome will be assessed on Radiographic Assessment.Timepoint: At 6 months.

Countries

India

Contacts

Public ContactDr Vijay Kumar

Deaprtment of Conservative Dentistry and Endodontics Himachal Dental College and Hospital

drshwetaverma053@gmail.com9418476681

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026