Randomized Cross-Over Study Evaluating the Efficacy of an Advanced Janu Basti Yantra Compared with the Classical Janu Basti Method Using Dhanvantara Taila in Knee Osteoarthritis (Janusandhigata Vata).

Efficacy of an Advanced Janu Basti Yantra Compared with the Classical Janu Basti Method Using Dhanvantara Taila in the Treatment of Knee Osteoarthritis (Janusandhigata Vata): A Randomized Cross-Over Study - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109050

Enrollment

Registered

2026-04-22

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Knee Osteoarthritis as defined Grade I to Grade III of the Kellgren and Lawrence scale with average pain intensity above 4 as measured by Visual Analogue Scale (VAS). Patients having complaints of: 1.Janusandhi shula ( Knee joint pain ) 2.Janusandhi shotha ( Swelling of knee joint ) 3.Akunchana prasaran kashtata (Restricted joint movement)

Exclusion criteria

Exclusion criteria: Patients with known case of:- 1.Aamvata ( Rheumatoid Arthritis ) 2.Vatarakta ( Gout ) 3.History of total knee replacement surgery 4.Treatment with opioid analgesics 5.Complete loss of knee articular and ligament tear 6.Knee dislocation 7.Knee Injury 8.Contact dermatitis

Design outcomes

Primary

Measure	Time frame
Design and development of the Advanced Janu Basti Yantra, including successful fabrication, functional validation, and standardization of the device for controlled administration of Janu Basti therapy (e.g., temperature maintenance, oil retention, and ease of application).Timepoint: 5 weeks	—

Secondary

Measure	Time frame
Change in Pain, knee stiffness and functional outcomes, assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale, measured as the difference between baseline and post-treatment scores in patients with Knee Osteoarthritis (Janusandhugata Vata).Timepoint: 7th, 15th, 21st Day;Changes in knee joint range of motion (ROM) following each intervention using Goniometer.Timepoint: 7th, 15th, 21st day;Change in knee joint swelling (Shotha), assessed using knee girth measurement at standardized anatomical landmarks, measured from baseline to post-treatment values in patients with Knee Osteoarthritis (Janusandhigata Vata).Timepoint: 7th, 15th, 21st day;Patient-reported comfort and tolerability, assessed using a patient-reported comfort scale, measured as total comfort score at the end of the treatment period and compared between the Advanced Janu Basti Yantra and Classical Janu Basti groups in patients with Knee Osteoarthritis (Janusandhigata Vata).Timepoint: 7th, 15th, 21st day;Incidence and type of procedure-related adverse events recorded during the treatment period and compared between the Advanced Janu Basti Yantra and Classical Janu Basti groups in patients with Knee Osteoarthritis (Janusandhigata Vata).Timepoint: 7th, 15th, 21st day	—

Measure

Time frame

Change in Pain, knee stiffness and functional outcomes, assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale, measured as the difference between baseline and post-treatment scores in patients with Knee Osteoarthritis (Janusandhugata Vata).Timepoint: 7th, 15th, 21st Day;Changes in knee joint range of motion (ROM) following each intervention using Goniometer.Timepoint: 7th, 15th, 21st day;Change in knee joint swelling (Shotha), assessed using knee girth measurement at standardized anatomical landmarks, measured from baseline to post-treatment values in patients with Knee Osteoarthritis (Janusandhigata Vata).Timepoint: 7th, 15th, 21st day;Patient-reported comfort and tolerability, assessed using a patient-reported comfort scale, measured as total comfort score at the end of the treatment period and compared between the Advanced Janu Basti Yantra and Classical Janu Basti groups in patients with Knee Osteoarthritis (Janusandhigata Vata).Timepoint: 7th, 15th, 21st day;Incidence and type of procedure-related adverse events recorded during the treatment period and compared between the Advanced Janu Basti Yantra and Classical Janu Basti groups in patients with Knee Osteoarthritis (Janusandhigata Vata).Timepoint: 7th, 15th, 21st day

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Countries

India

Contacts

Public ContactDr Snehal Aldar

Dr. D. Y. Patil College of Ayurved and Research Centre, Pimpri, Pune 411018.

pranesh.gaikwad@dpu.edu.in8149861128

Outcome results