Health Condition 1: J459- Other and unspecified asthma
Conditions
Interventions
Intervention1: levosalbutamol nebulization: nebulized levosalbutamol at 0.075mg/kg/dose (minimum 1.25mg, maximum of 5 mg). Nebulisations will be administered every 20 minutes interval(3 times in an ho
Sponsors
Mahatma Gandhi Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. All children of age group between 5 to 16 years who present with an acute exacerbation of bronchial asthma and having an modified Pulmonary Index Score of less than 6 2. Children of parents who provide consent to let them participate in the study.
Exclusion criteria
Exclusion criteria: 1. All the children having modified Pulmonary index score more than 6. 2. Children already on preventive therapy (steroids plus or minus LABA). 3. Cyanotic or uncorrected CHD. 4. Cystic fibrosis or any other chronic lung disease. 5. Patient on treatment diuretics, aminoglycosides, bicarbonates. 6. Patient with hepatic, pre-existing renal disease, acute gastroenteritis. 7. Known case of hypersensitivity to salbutamol OR levosalbutamol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of levosalbutamol with salbutamol by calculating Modified Pulmonary Index Score (mPIS) and peak expiratory flow rate (PEFR) after nebulization using either drug. Timepoint: Outcome like Modified Pulmonary Index Score (mPIS) and peak expiratory flow rate (PEFR) will be assessed after nebulization using either drug. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the adverse effects of levosalbutamol & salbutamol by a. Estimation of serum potassium levels b. Clinical parameters like Spo2 & HR at baseline & 1 hour post-nebulization. Timepoint: Outcome like potassium levels HR Spo2 will be seen at Baseline followed by 1 hour post nebulization | — |
Countries
India
Contacts
Public ContactDarshil Shah
mahatma gandhi medical college hospital sitapura jaipur
Outcome results
None listed