Health Condition 1: H741- Adhesive middle ear disease
Conditions
Interventions
Intervention1: 10% MESNA: Topical application of 10% MESNA soaked gel foam in middle ear during surgery
Control Intervention1: Normal saline: Topical application of Normal saline soaked gel foam in m
Sponsors
Dr Suktara Sharma
Dr Akta vasani
Eligibility
Inclusion criteria
Inclusion criteria: Patients with adhesive otitis media
Exclusion criteria
Exclusion criteria: Patients with central perforation Patients with uncontrolled systemic disease History of previous ear surgery of the same ear Active infection in the ear
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ease of elevation of adherent tympanic membrane and epithelium from underlying bone or the ossicular chain compared to traditional mechanical dissection.Timepoint: During surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study the safety profile of MESNA in terms of inner ear damage 2.To study the safety profile of MESNA in terms facial nerve dysfunction 3.To evaluate the rate of mucosal preservation over promontory using MESNA v/s conventional dissection 4.To evaluate the rate of iatrogenic ossicular injury using 10% MESNA vs conventional dissection 5.Comparison of hearing outcome post surgery b/w two groups Timepoint: At the time of surgery and upto 3 months after surgery | — |
Countries
India
Contacts
Public ContactDr Suktara Sharma
GCS Medical college Hospital and Reserch Center
Outcome results
None listed