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The Importance of Heart Function in Patients with Severe Respiratory Failure on Ventilators.

Diagnostic and Prognostic Value of Ventricular Strain in Mechanically Ventilated Individuals with Acute Respiratory Distress Syndrome. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108994
Enrollment
124
Registered
2026-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J80- Acute respiratory distress syndrome

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Manipal Academy of Higher Education
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Individuals older than or equal to 18 years diagnosed with ARDS, admitted to the ICU on invasive mechanical ventilation. 2. Adequate echocardiographic image quality permitting strain analysis

Exclusion criteria

Exclusion criteria: 1. History of significant cardiac disease (LVEF less than 50%, known IHD/Structural heart disease/cardiac transplant/ arrhythmias/ Known RV dysfunction). 2. Severe PAH on treatment 3. Use of ECMO at the time of imaging/ Prone individuals on IMV. 4. Lung carcinoma. 5. Pregnant individuals. 6. Cardiac tamponade or pericardial effusion more than mild. 7. Chronic Kidney Disease(CKD-5) / Liver disease (CLD/DCLD). 8. Bystander not willing to consent to the study.

Design outcomes

Primary

MeasureTime frame
Right ventricular strain Timepoint: during ventilation, during changes in ventilation pressures and after removal of ventilation

Secondary

MeasureTime frame
Left ventricular global longitudinal strain Left ventricular diastolic dysfunction. Impact of pulmonary hypertension on ventricular strain.Timepoint: during ventilation, during changes in ventilation pressures and after removal of ventilation

Countries

India

Contacts

Public ContactDr Krishnanada Nayak

Manipal College of Health Professions, MAHE, Manipal

krishnananda.n@manipal.edu9964015487

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026