FindTrial
Sign In

Influence of Antihypertensive Medications on Blood Pressure Changes During Spinal Anaesthesia

ASSOCIATION OF ANTIHYPERTENSIVE THERAPY ON SPINAL ANAESTHESIA-INDUCED HYPOTENSION - A PROSPECTIVE OBSERVATIONAL STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108984
Enrollment
96
Registered
2026-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals aged 20 to 65 years will be included in the study Including abdominal, urological and orthopaedic surgeries Elective spinal cases

Exclusion criteria

Exclusion criteria: Pregnant women Long-term Diabetes patients (greater than10 years) Severe neurological diseases (Autonomic failure, Multiple system atrophy) Severe cardiovascular diseases (Aortic stenosis, Heart failure)

Design outcomes

Primary

MeasureTime frame
This study compares the incidence of spinal anaesthesia induced hypotension among the three groups, based on the duration of antihypertensive therapy The study will evaluate the incidence of bradycardia and the treatment administered, including the types of drugs used Assess the severity of hypotension in each group and compare the vasopressor requirements and the volume of intravenous fluids used. The study will evaluate the effect of diabetes as a coexisting condition on the occurrence of hypotension.Timepoint: Recording baseline blood pressure and document the type and duration of antihypertensive therapy. After giving Spinal anaesthesia, monitoring blood pressure every 3 minutes for the first 30 minutes and every 5 minutes for the rest 1hour minutes to detect hypotension.—

Secondary

MeasureTime frame
To assess the severity of spinal anaesthesia induced hypotension among the study groups. To compare the vasopressor requirement and intravenous fluid usage among the groups. To evaluate the influence of diabetes as a coexisting disease on the occurrence of hypotension.Timepoint: Recording baseline blood pressure and document the type and duration of antihypertensive therapy. After giving Spinal anaesthesia, monitoring blood pressure every 3 minutes for the first 30 minutes and every 5 minutes for the rest 1hour minutes to detect hypotension.—

Countries

India

Contacts

Public ContactKajal R Shetty

Kasturba Medical College Mangalore - MAHE

kajal.shetty@manipal.edu8073814280

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026