Health Condition 1: K352- Acute appendicitis with generalized peritonitis Health Condition 2: N700- Acute salpingitis and oophoritis Health Condition 3: N400- Benign prostatic hyperplasia without lower urinary tract symptoms Health Condition 4: K402- Bilateral inguinal hernia, withoutobstruction or gangrene Health Condition 5: N200- Calculus of kidney Health Condition 6: N201- Calculus of ureter Health Condition 7: N711- Chronic inflammatory disease of uterus Health Condition 8: K650- Generalize
Conditions
Interventions
Intervention1: Buprenorphine: Drug
Intervention2: Hyperbaric Bupivacaine Heavy: Drug for Spinal Anaesthesia in the dose of 12.5 milligram which is 2.5 millilitre in the form of 0.5 percent Hyperbaric
Sponsors
Regional Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18 to 60 years of either sex undergoing spinal anaesthesia for elective infraumbilical surgeries, such as surgical procedures on lower abdomen, genitourinary region including gynaecological and urological surgeries 2. Patients of American Society of Anaesthesiologists (ASA) grade 1 or 2 3. Either sex
Exclusion criteria
Exclusion criteria: 1. Pregnancy and lactation 2. Uncooperative patient and patient refusal to give consent 3. Patient with history of allergy to the drugs(hyperbaric Bupivacaine, Fentanyl, Buprenorphine) 4. Patients with uncontrolled diabetes mellitus, uncontrolled hypertension, uncontrolled thyroid disorder, height more than 180 cm or height less than 140 cm and weight more than 110 kgs or weight less than 45 kgs 5. Patients with cardiovascular, respiratory, renal, hepatic or neurological disease 6. Patients contraindicated for spinal anesthesia such as local site infection, spinal deformity, patient with bleeding disorder-platelet count more than 50000/microliter, prothrombin time ore than 14 seconds, INR more than 1.5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the duration of analgesia between the study groupsTimepoint: After the intrathecal injection, parameters as per the protocol will be recorded every 2 minutes for the first 10 minutes and every 5 minutes till 30 minutes and every 10 minutes till 60 minutes and every 30 minutes till 180 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the onset time of sensory & motor block between the the two groups 2. To assess the duration of sensory & motor block achieved with each adjuvant 3. To assess the hemodynamic stability 4. To identify the adverse effectsTimepoint: After the intrathecal injection every parameters as per the protocol will be recorded every 2 minutes for the first 10 minutes & every 5 minutes till 30 minutes & every 10 minutes till 60 minutes & every 30 minutes till 180 minutes | — |
Countries
India
Contacts
Public ContactMaharambam Binarani
Regional Institute of Medical Sciences
Outcome results
None listed