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Does the Strength of Root Canal Cleaning Solution Affect Pain After Treatment?

Effect of Different Sodium Hypochlorite Concentrations on Postoperative Pain in Single-Visit Root Canal Treatment of Mandibular Molars with necrotic pulp- A randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108951
Enrollment
165
Registered
2026-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: sodium hypochlorite in three different concentration: Group 1: 1% sodium hypochlorite Group 2: 3% sodium hypochlorite Group 3: 5.25% sodium hypochlorite Intervention2: 1% sodium hyp

Sponsors

Abdu Semeer Palottil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy male and female patients, aged between 18 and 50 years Mandibular molar with necrotic pulp. Respond negatively to vitality test. Radiograph shows no periapical radiolucency

Exclusion criteria

Exclusion criteria: Analgesics taken 12 h before treatment, Severely curved root canal, Acute periapical or periodontal abscess, Badly decayed crowns, Pregnant and lactating, Allergies to materials/medications used

Design outcomes

Primary

MeasureTime frame
Post operative painTimepoint: 6, 12 24 48 hours after the proedure—

Secondary

MeasureTime frame
Analgesic intake : Timepoint: Patients will be informed to record the amount of analgesics consumed in numbers in 1st to 7 days—

Countries

India

Contacts

Public ContactAbdu Semeer Palottil

Govtt Dental College Kozhikode

drabdusemeerpalottil@gmail.com8907566651

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026