Health Condition 1: O244- Gestational diabetes mellitus
Conditions
Interventions
Intervention1: tab metfromin 500mg: tab metformin 500mg BD and it will be increased as needed up to 2 gm/day at 15 days
Intervention2: injection inuslin: subcutaneous insulin will be started including
Sponsors
Adeeba Naseem
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant women diagnosed with GDM before 24 weeks of gestation. Pregnant women with a singleton pregnancy
Exclusion criteria
Exclusion criteria: Pregnant women with pre-existing type 1 or type 2 diabetes 2. Pregnant women with multiple gestations (e.g., twins, triplets). 3. Pregnant women with severe medical conditions that may affect glucose metabolism or fetal growth (e.g., chronic kidney disease, liver disease). 4. Pregnant women with PCOS on Metformin. 5. Pregnant women with a known allergy or intolerance to metformin or insulin. 6. Pregnant women currently taking medications that may interact with metformin or insulin (e.g., corticosteroids, beta-blockers). 7. Pregnant women with known fetal anomalies or congenital abnormalities. 8. Pregnant women who do not give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the effectiveness of metformin vs insulin in achieving target blood glucose levels in pregnant women with early GDM.Timepoint: 2 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the impact of metformin and insulin on maternal outcomes. To compare the impact of metformin and insulin on fetal outcomes Timepoint: 18 months | — |
Countries
India
Contacts
Public ContactProf Nishat Akhtar
jawaharlal nehru medical college and hospital aligarh muslim university
Outcome results
None listed