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Comparison of currently used and modified numbing injections to assess pain relief during removal of lower back teeth in adults.

A Comparative Evaluation Of Buffered Articaine Buccal Infiltration Versus Conventional Inferior Alveolar Nerve Block Using 2 percent Lignocaine In Mandibular Molar Extractions - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108928
Enrollment
60
Registered
2026-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: Intraoral Buccal Infiltration Injection using Buffered Articaine for anesthetising Mandibular Molars: Buffered Articaine Preparation The preparation will be started immediately before
0.17 ml of the solution will be withdrawn from the 1.7ml 4% Articaine with Adrenaline (1:100,000) Cartridge. This withdrawn solution will be used for intradermal Allergy testing. Then using another In

Sponsors

Dr. C. N. Srinivas
Lead Sponsor
Dr Tejaswini PSS
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Physically healthy (ASA I) patients reporting to the OMFS Department at Malla Reddy Institute of Dental Sciences, Hyderabad, planned for extraction of mandibular molars, indicated due to fracture, caries, or periodontal pathology, and with no known allergy to amide or ester local anaesthetics or sulphites.

Exclusion criteria

Exclusion criteria: Patients with underlying medical comorbidities, those who have undergone radiotherapy or chemotherapy within the past 12 months, patients on medications such as antiplatelets, anticoagulants, antihypertensives, antidiabetics, or steroids, individuals with habits of smoking or alcohol abuse, pregnant or lactating women, patients with a known history of allergy to local anaesthetics, sulphites, or adrenaline, those presenting with ulcers, extraoral trauma, TMJ disorders, MPDS, trigeminal neuralgia, or referred pain from sinus or ear, and patients unwilling to participate in the study.

Design outcomes

Primary

MeasureTime frame
Intraoperative pain in both the groupsTimepoint: At baseline—

Secondary

MeasureTime frame
Pain on injectionTimepoint: While depositing the solution;Onset of AnaesthesiaTimepoint: Within few minutes after injecting the solutions;Need for supplemental injectionTimepoint: During the procedure;Incidence of anaesthetic related complicationsTimepoint: Upto 48hrs;Duration of anaesthesiaTimepoint: On same Day—

Countries

India

Contacts

Public ContactShardul Sunil Kaluke

Malla Reddy Institute of Dental Sciences, Hyderabad

srinivasomfs@gmail.com9849356046

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026