Health Condition 1: E210- Primary hyperparathyroidism
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Manipal Academy of Higher Education
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged more than 18 years, presenting to the Endocrine OPD referred for echocardiography, with diagnosed Primary Hyperparathyroidism with persistent hypercalcemia and elevated PTH levels 2.Candidates scheduled for curative parathyroidectomy 3.Written informed consent for participation and echocardiographic assessments pre and post operatively
Exclusion criteria
Exclusion criteria: 1.Pre-existing significant heart conditions like CAD, valve disease with moderate to severe MS or AS, arrhythmias, or severe heart failure 2.Major systemic or endocrine issues likr parathyroid carcinoma, MEN, advanced kidney disease, BMI more than 28, uncontrolled diabetes or thyroid 3.Recent medication changes or use of cardiotoxic or unstable high-dose drugs 4. Inadequate ECHO window
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of this study is to evaluate changes in left ventricular structure and function in patients with primary hyperparathyroidism before and after parathyroidectomy, as assessed by 3D echocardiography. Key parameters will include left ventricular ejection fraction, left ventricular mass, ventricular volumes, and indices of systolic and diastolic function.Timepoint: The primary outcome of this study is to evaluate changes in left ventricular structure and function in patients with primary hyperparathyroidism before parathyroidectomy at 1 week and after parathyroidectomy at 12 weeks , as assessed by 3D echocardiography | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Krishnananda Nayak
Manipal college of Health Professions
Outcome results
None listed