Health Condition 1: I959- Hypotension, unspecified
Conditions
Interventions
Intervention1: Push dose Epinephrine: Patients will receive intravenous push-dose epinephrine (20 mcg) immediately prior to rapid sequence intubation, along with standard care. Rapid sequence intubati
Sponsors
Dr. Minhaj Arif
Eligibility
Inclusion criteria
Inclusion criteria: l)Patients aged 16 years or more requiring emergent orotracheal intubation in the emergency department setting. 2)Patients having systolic blood pressure (SBP) less than 100 mm Hg, diastolic blood pressure (DBP) less than 60 mm Hg, or mean arterial pressure (MAP) less than 65 mm Hg
Exclusion criteria
Exclusion criteria: 1)Pregnancy 2)Vasopressor infusion at time of evaluation 3)Patients who are brought in cardiac arrest to the Emergency room 4)Who denied consent for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of peri-intubation hypotension, defined as systolic blood pressure (SBP) less than 90 mmHg or mean arterial pressure (MAP) less than 65 mmHg within 30 minutes of endotracheal intubation.Timepoint: From time of intubation to 30 minutes post-intubation, recorded at baseline and every 5 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of cardiac arrestTimepoint: Within 30 minutes of intubation;Incidence of adverse events (dysrhythmia and drug extravasation)Timepoint: Within 30 minutes of intubation;Requirement of additional vasopressor supportTimepoint: Within 30 minutes of intubation;24 hour mortalityTimepoint: At 24 hours post-intubation | — |
Countries
India
Contacts
Public ContactDr Divendu Bhushan
AIIMS Patna
Outcome results
None listed