Health Condition 1: C579- Malignant neoplasm of female genital organ, unspecified
Conditions
Interventions
Intervention1: BMI based PEEP: PEEP setting in the intervention arm would be done as per the BMI of the patient. this is the new proposed method, being compared to the standard of care technique for P
Sponsors
All India institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: ASA Physical Status I or II or III BMI 18 - 40 Kg/m2 Scheduled for elective laparoscopic gynecological surgery under general anaesthesia. Informed consent
Exclusion criteria
Exclusion criteria: Pre- existing lung disease (COPD, ARDS, fibrosis) Pregnancy Emergency or open surgery MAP less than 65 mmHg or need for vasopressors prior to induction Contraindication to PEEP ( eg., pneumothorax, severe pulmonary hypertension) Refusal or inability to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the mean intraoperative driving pressure between Compliance titrated PEEP and BMI- based PEEPTimepoint: Every 30 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare lung aeration using Lung Ultrasound Score(LUS). To measure perioperative respiratory complian(Crs) To evaluate intraoperative haemodynamic stability including mean arterial pressure (MAP), vasopressors requirement To assess perioperative oxygenation parameters including postoperative SpO , PaO , PaO /FiO ratio. To identify the incidence of postoperative pulmonary complications(PPCs). Timepoint: Every 30 minutes intraoperatively And 30 minutes after postoperative | — |
Countries
India
Contacts
Public ContactDr Dhilip Kumar E
All India institute of medical sciences
Outcome results
None listed