HD-tDCS in management of cognitive symptoms in depressive disorder

To determine the efficacy of high definition transcranial direct current stimulation (HD-tDCS) as an adjunct in management of cognitive symptoms in major depressive disorder: A single-blind randomized controlled trial from north Karnataka - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108838

Enrollment

Registered

2026-04-20

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F329- Major depressive disorder, singleepisode, unspecified

Interventions

Intervention1: HD-tDCS: Sham controlled trial Intervention2: High Definition transcranial direct current stimulation: High-Definition Transcranial Direct Current Stimulation (HD-tDCS) will be administ

Eligibility

Inclusion criteria

Inclusion criteria: patients willing and able to give written informed consent Diagnosis of major depressive disorder as defined by DSM-5 patients on stable antidepressant medications for atleast 4 weeks prior to enrollment

Exclusion criteria

Exclusion criteria: Patients who refuse to consent for study History of neurocognitive disorders or severe psychiatric disorders other than MDD Bipolar depression, psychotic depression Pregnancy or breastfeeding Metal implants in head Skin lesions over the stimulation site History of seizures or epilepsy Patients who had previously undergone any neuromodulation techniques including ECT in the last 6 months

Design outcomes

Primary

Measure	Time frame
To determine the Efficacy of High definition Transcranial direct current stimulation as an adjunct in management of cognitive symptoms in major depressive disorder using MOCA scaleTimepoint: Over a period of 12 months	—

Secondary

Measure	Time frame
To determine the Efficacy of High definition Transcranial direct current stimulation as an adjunct in management of over all depressive symptoms using MADRSTimepoint: over a period of 12 months	—

Countries

India

Contacts

Public ContactDrSameer Belvi M

Karnataka medical College and research institute Hubli

sameerbelvi@gmail.com9845612224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026