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A Study to See How Different Amounts of Dexmedetomidine Improve Spinal Anesthesia for Lower Abdominal Operations

A Study to Observe Effect of Different Doses of Dexmedetomidine as an Adjuvant to Hyperbaric Bupivacaine for Spinal Anaesthesia in Patients undergoing Lower Abdominal Surgery - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108802
Enrollment
100
Registered
2026-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N219- Calculus of lower urinary tract, unspecified

Interventions

Intervention1: Bupivacaine + Dexmedetomidine (10mcg): Route of administration intrathecal 10mcg Dexmedetomidine diluted in 0.5ml normal saline+ 0.5% bupivacaine (3ml) with total of 3.5 ml volume Contr

Sponsors

Gujarat Cancer Society Medical Hospital And Research Centre Ahmedabad Gujarat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 and 2 Patients of 18-60 years of either gender Patients posted for elective lower abdominal surgeries

Exclusion criteria

Exclusion criteria: ASA Grade 3 and 4 Patient refusal Hypersensitivity to study drug Infection at the site of injection Presence of bleeding disorder disorder Severe hypotension, bradycardia, severe aortic/mitral stenosis Raised intracranial tension Head injury Patient receiving other modes of intraoperative analgesia Pregnant females Patient with neurological disorder and deficit, spinal cord and peripheral nerve diseases, poliomyelitis, multiple sclerosis Patient on alpha adrenergic antagonists, Ca channel blockers, angiotensin converting enzyme inhibitors

Design outcomes

Primary

MeasureTime frame
Duration of AnalgesiaTimepoint: 1 hour 2 hour 3 hour 6 hour 9 hour

Secondary

MeasureTime frame
Pulse Systolic Blood Pressure Diastolic Blood Pressure spo2Timepoint: 0 min 5 min 10 min 15 min 20 min 25 min 30 min 60 min 90 min 120 min

Countries

India

Contacts

Public ContactKrimi Patel

GCS Medical College Hospital Research Centre Ahmedabad

asmivip@yahoo.co.in9879006601

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026