FindTrial
Sign In

A study comparing the effect of a pain-relief medicine given through a vein versus the spine to improve comfort after lower body surgery.

Efficacy of adjuvant effect of intravenous vs intrathecal dexmedetomidine on 0.5%Hyperbaric levobupivacaine for postoperative analgesia in patients undergoing lower abdominal and lower limb surgeries under Subarachnoid block- a prospective double blinded randomised controlled study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108801
Enrollment
75
Registered
2026-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration Health Condition 2: N433- Hydrocele, unspecified

Interventions

Intervention1: Dexmedetomidine: NA Intervention2: Dexmedetomidine 10microgram with 3.4ml of 0.5% hyperbaric levobupivacaine: Intrathecal route Control Intervention1: Dexmedetomidine 0.5microgram/kg in

Sponsors

The Dean
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients under American society of Anaesthesiologist classification of class I & II Posted for elective lower abdominal and lower limb surgeries

Exclusion criteria

Exclusion criteria: Coagulation abnormalities Bleeding disorder Spine deformity Cardiac /renal disease Drug allergy

Design outcomes

Primary

MeasureTime frame
Duration of analgesia between two administration routesTimepoint: 0 minutes 3 minutes 5 minutes then every 15 minutes—

Secondary

MeasureTime frame
Onset of motor block Onset of sensory block Time taken for 2 point regression Duration of sensory blockade Duration of motor blockade Timepoint: 0 minutes 3 minutes 5 minutes then every 15 minutes until 2hrs & every 1 hr post surgery—

Countries

India

Contacts

Public ContactPriyanka Sakthivel

Chettinad hospital and research institute

pugalenthi08@yahoo.co.in9489404818

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026