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A Pilot Study on the Comparative Accuracy of DASI, Six-Minute Walk Test, Incremental Shuttle Walk Test and CPET in Healthy Asian Volunteers

Comparative Validation of DASI score, 6WMT and ISWT with Cardiopulmonary Exercise Testing in healthy volunteers: A Pilot Analysis on objectifying clinical insights - VALIDATE Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108741
Enrollment
50
Registered
2026-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C00-D49- Neoplasms

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

ACTRECTMC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy volunteers belonging to Asian population without any co-morbidities. Healthy volunteers will primarily be recruited through voluntary participation from hospital staff, students, anaesthesia/OT technicians associated with the institution after director s approval

Exclusion criteria

Exclusion criteria: 1. Any lower limb fracture or other comorbidity which restricts walking and cycling. 2. BMI above 25 kg/m2, 3. Participant with chronic history of smoking 4. Individual having cognitive decline. 5. Refusal to consent

Design outcomes

Primary

MeasureTime frame
The primary aim of our study is to compare which amongst the subjective functional tests DASI, 6MWT and ISWT would show best positive correlation with VO2peak recorded by CPET findings in healthy individuals.Timepoint: Readings of the mentioned parameters will be recorded at the start (0 mins) and end of each functional test and continuously for the duration of CPET. 6MWT at baseline (0 mins), after completion of test at 6 mins or before if the patient is fatigue ISMWT at baseline (0 mins), after completion of test at 12 mins or before if the patient is fatigue CPET at baseline (0 mins), continuously during the test after completion of test at 12 mins or before if the patient is fatigue.

Secondary

MeasureTime frame
To assess agreement between METs calculated by CPET & those estimated by each of the following: a.DASI -Hlatky equation b.6MWT-Burr equation c.ISWT -Singh equation Timepoint: METs will be assessed at the end of completion of each test. After filling questionnaire for DASI, after 6 mins for 6MWT, after 12 mins for ISWT & CPET;To record symptom-limited terminations & fatigability Borg RPE at the end of each of these exercise tests.Timepoint: Symptom-limited terminations & fatigability Borg RPE will be recorded after 6 mins for 6MWT, after 12 mins for ISWT & CPET or prior for symptom related termination

Countries

India

Contacts

Public ContactDr Vatsala Bagri

Tata Memorial Hospital

ssardeshpande28@yahoo.in9822240937

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026