Comparison of Two ways of giving Dexmedetomidine with Bupivacaine for better pain relief during Upper limb surgery using a Nerve Block

Comparative Evaluation of Intravenous and Perineural Dexmedetomidine as adjuvent along with Bupivacaine in Supraclavicular Brachial Plexus Block in upper limb surgery - a Prospective Randomised Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108699

Enrollment

Registered

2026-04-20

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S520- Fracture of upper end of ulna Health Condition 2: S521- Fracture of upper end of radius Health Condition 3: S581- Traumatic amputation at level between elbow and wrist Health Condition 4: S518- Open wound of forearm

Interventions

Intervention1: Intravenous and Perineural Dexmedetomidine as adjuvent along with Bupivacaine in Supraclavicular Brachial Plexus Block in upper limb surgery: One group will receive USG guided supraclav

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II , Weight between 45 and 75kg , patient willing to participate and undergoing Upper Limb surgery

Exclusion criteria

Exclusion criteria: Patient unwilling to participate , any history of allergy to any drug used , coagulopathy , local site infection

Design outcomes

Primary

Measure	Time frame
Time of onset and duration of sensory and motor blockade will be compared in both group.Timepoint: T0 - Time of administration of block T1 - Time of onset of sensory blockade T2 - Time of onset of motor blockade T3 - Total duration of blockade	—

Secondary

Measure	Time frame
1.The interval to first analgesic demand & cumulative analgesic dose over 24 hours will be recorded in both group using VAS scale 2.Level of sedation will be compared between both group using Ramsay sedation scale.Timepoint: T0 - Time of administration of first rescue analgesic Qt - Total cumulative dosage of rescue analgesic within 24 hours of blockade	—

Countries

India

Contacts

Public ContactPrabhat Kumar

Rajendra Institute of Medical Sciences

bhagatmanisha7@gmail.com9386269477

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026