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study to assess whether a clinical scoring system and blood test can predict failure of non invasive ventilation in patients with severe breathing difficulty

Evaluation of the Heart rate Acidosis Consciousness Oxygenation Respiratory rate HACOR Score as a Predictor of Non-Invasive Ventilation Failure in Patients with Hypoxemic Respiratory Failure - Heart rate Acidosis Consciousness Oxygenation Respiratory rate

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108656
Enrollment
72
Registered
2026-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

Intervention1: Nil: Nil

Sponsors

Jawaharlal Nehru Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients above age of 18 years admitted in medical intensive care unit requiring non-invasive ventilation fulfilling the criteria of Hypoxemic Respiratory failure: 1)Partial pressure of oxygen( PA02) 2)Partial pressure of carbon dioxide (PACO2)- Normal/Decreased

Exclusion criteria

Exclusion criteria: 1)Pregnancy 2)Patients who directly require Mechanical ventilation. 3)Hypercapnic Respiratory failure. 4)Patients who underwent the use of non-invasive ventilation after extubation. 5)Patient who had undergone non-invasive ventilation more than 2hrs before being admitted in medical intensive care unit. 6)Upper airway obstruction.

Design outcomes

Primary

MeasureTime frame
1. Change in HACOR score between 0 and 24 hours. 2. Correlation between HACOR score and NIV failure.Timepoint: 0 and 24 hours.—

Secondary

MeasureTime frame
1. Incidence of NIV failure 2. ICU length of stay 3. ICU mortality 4. Hospital mortalityTimepoint: 0 and 24 hrs, till discharge or death—

Countries

India

Contacts

Public ContactMOHINI RAMAKANT PATIL

Jawaharlal Nehru Medical College

metgudanjali@gmail.comO8312437769

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026