Health Condition 1: - Health Condition 2: A419- Sepsis, unspecified organism
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
Max superspeciality hospital
Eligibility
Inclusion criteria
Inclusion criteria: Age between 18 years to 70 years Patients admitted to ICU fulfilling the SIRS criteria Consent will be taken from the patient attendant if the patient will not be fit to give consent.
Exclusion criteria
Exclusion criteria: Pregnant women Individuals transferred from other hospitals or wards Patients with untreated end stage renal failure not on dialysis, medullary thyroid carcinoma, or islet cell tumors. Severe pancreatitis, post liver transplant, severe and prolonged cardiogenic shock, or heat shock. Patients on immunosuppressants/ immunomodulators. Patients unwilling to consent. Prior antibiotic use before blood culture sampling. Patients who will be admitted to the department more than once during the inclusion period will be counted only once, at the time of their initial admission, and not again during future admissions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prediction accuracy of PCT, CLR, CRP, and NLR for bacteremia.Timepoint: baseline, day 5 | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of PCT, CLR, CRP, & NLR levels between Gram-positive & Gram-negative bacteremia. Determination of the optimal cut-off values of PCT, CRP, NLR, & CLR for predicting bacteremia in the Indian ICU population. Determination of the sensitivity, specificity, positive predictive value (PPV), & negative predictive value (NPV) of these markers individually for predicting bacteremia in the Indian ICU population.Timepoint: baseline, on day 5 | — |
Countries
India
Contacts
Public ContactDr Deepshikha Maharshi
Max Super Speciality Hospital, Sector 128, Noida
Outcome results
None listed