Comparing the Effect of Bone Graft, Laser, and Advanced Platelet-Rich Fibrin in Periodontal Bone Regeneration

Comparative Evaluation of Nanohydroxyapatite Bone Graft and Laser Therapy with and without Advanced Platelet Rich Fibrin in the Treatment of Periodontal Intrabony Defects - A Randomized Clinical Trail - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108632

Enrollment

Registered

2026-04-20

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Laser Therapy,Nanohydroxyapatite Bone Graft: Diode laser wavelenght of 980nm,1.0 W power and 50ms in pulsating mode. B-Ostin HA nano-crystalline bone substitute with particle size of 0.

Eligibility

Inclusion criteria

Inclusion criteria: Participants of either sex with good oral hygiene having platelet count within normal limits Presence of atleast one or two sites with probing pocket depth of greater than or equal to 5 mm Presence of periodontal intrabony defects greater than or equal to 3 mm Participants with good oral hygiene compliance after phase I therapy

Exclusion criteria

Exclusion criteria: Systemic diseases affecting periodontal healing. Smokers and any form of tobacco users. Pregnant or lactating women. Teeth with any type of tooth mobility. Previous periodontal surgery in the selected site within 6 months. Participants allergic to local anaesthesia, chlorhexidine,antibiotics and analgesics.

Design outcomes

Primary

Measure	Time frame
Reduction in probing pocket depth Gain in clinical attachment level Radiographic bone fillTimepoint: Baseline,1 week,6 months,9 months	—

Secondary

Measure	Time frame
Changes in plaque index To check for Bleeding on Probing using Modified Sulcular Bleeding IndexTimepoint: Baseline,1 week,6 months,9 months	—

Countries

India

Contacts

Public ContactDr.Vanditha Dasari

Narayana Dental College And Hospital,Nellore

vandithadasari531@gmail.com9398459519

Outcome results