One-Year Comparison Using 3D Dental Scans Healing of Root Tip Infections in Multi-Rooted Dead Teeth Treated with Sound Wave Irrigation, High Frequency Vibration Irrigation, or Standard Needle Irrigation after Continuous Softening of Tooth Material a Single-Blind Randomized Trial

One-year Comparative CBCT based evaluation of Periapical healing with ultrasonic activation, sonic activation and Conventional side -vented needle following continuous chelation irrigation protocol in non-vital multi - rooted teeth: A single blinded Randomized clinical study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108583

Enrollment

Registered

2026-04-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Ultrasonic activation: Ultrasonic activation, one of the most widely used activation systems having frequency of 25-30 kHz. It creates an acoustic flow by providing hydrodynamic activat

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients (Category: American Society of Anaesthesiologists class 1) (ASA House of Delegates 2014) aged between 18 60 years of age with maxillary or mandibular teeth which are multi rooted will be included in the study. 2. Maxillary or mandibular teeth having CBCT Periapical Index (PAI) Score 3 or more (according to CBCT- PAI score classification) will be included. 3. Patients having sinus tract opening and sign of pus discharge will be included in study. 4. Only those patients ready to sign the consent form will be included in the study.

Exclusion criteria

Exclusion criteria: Teeth with open apex, root resorption and calcified pulp chamber and canals will be excluded from the study. 2. Teeth with curvature more than 20 degree (according to Schneider s classification) will be excluded from the study. 3. Teeth which had received previous endodontic treatment will be excluded from the study. 4. Pregnant and lactating mothers will be excluded from the study. 5. Teeth with developmental anomaly or pathology or congenital defects will be excluded. 6. Periodontally compromised teeth having mobility, furcation involvement and pocket depth more than 4 mm will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
To compare periapical healing with ultrasonic activation, sonic activation, and conventional side vented needle irrigation following continuous chelation irrigation protocol in non-vital multi - rooted teeth baseline and one year using CBCT-PAI index.Timepoint: Baseline and one year	—

Secondary

Measure	Time frame
NilTimepoint: NIL	—

Countries

India

Contacts

Public ContactDrVishnu Pratap Singh Rathore

K M Shah Dental College

dr.vishnurathore84@gmail.com7575071175

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026