Health Condition 1: Z53- Persons encountering health services for specific procedures and treatment, not carried out
Conditions
Interventions
Intervention1: Injection Palonosetron: Injection Palonosetron 1 microgram per kg with a maximum dose of 75 micrograms intravenous given during induction
Control Intervention1: injection ondansetron: i
Sponsors
D Y Pati University School of Medicine and Hospital, Nerul, Navi Mumbai
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients scheduled to undergo Laparoscopic Surgery 2.Patients belonging to American Society of Anaesthesiologists (ASA) Grades I or II 3. Patients undergoing a surgery duration of less than 3 hours
Exclusion criteria
Exclusion criteria: 1.History of PONV or motion sickness 2. Allergy to study medications 3. Presence of existing GI disease or hiatal hernia 4. Pregnancy or lactation 5. Patient already on antiemetics, psychomimetics, steroids preoperatively or chemotherapeutic drugs in past few weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To compare ondansetron and palonosetron for number of incidences of Post operative Nausea and Vomiting via scoringTimepoint: at 0-2 hours 2-24 hours 24-48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the requirement of rescue antiemetics. Timepoint: at 0-2 hours 2-24 hours 24-48 hours;To assess incidence of adverse effectsTimepoint: at 0-2 hours 2-24 hours 24-48 hours | — |
Countries
India
Contacts
Public ContactDr Sunanda Panigrahi
D Y Patil University School of Medicine and hospital
Outcome results
None listed