Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: DEXMEDETOMIDINE IV: Inj DEXMEDETOMIDINE 0.5 MCG/KG IV over 10 minutes
Intervention2: KETAMINE IV: Inj KETAMINE 0.5 MG/KG IV bolus
Intervention3: MAGNESIUM SULPHATE IV: Inj MAGNESIUM SUL
Sponsors
JSS Academy Of Higher Education And Research
Eligibility
Inclusion criteria
Inclusion criteria: Patients of age 18 to 60 years of ASA grade 1, 2 and 3 undergoing elective surgery under spinal anaesthesia with grade 2 and above shivering
Exclusion criteria
Exclusion criteria: 1. Patients with ASA physical status above 3. 2. Patients allergic or contraindicated to study medication. 3. Patients with severe cardio pulmonary disease, renal or liver impairment, peri operative fever or hypothermia, history of seizure, massive blood transfusion and history of psychiatric illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of Dexmedetomidine, Ketamine, Magnesium Sulphate in the treatment of peri operative shivering subsequent to spinal AnesthesiaTimepoint: After study drug administration shivering grade will be assessed at 1, 3, 5 minutes and thereafter every 5 minutes till shivering resolves or 30 minutes has elapsed. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess the hemodynamic parameters after giving the study drugs. 2. To compare side effects of the drugs including nausea, vomiting, hypotension, hypertension, bradycardia, tachycardia, sedation, respiratory depression, delirium, hypothermia.Timepoint: After administration of the study drug all secondary outcomes will be assessed at 1, 3, 5 minutes & thereafter every 5 minutes till 30 minutes. | — |
Countries
India
Contacts
Public ContactDr Archana K N
JSS Academy Of Higher Education And Reasearch
Outcome results
None listed