Effect of dental cleaning using LASER on gum diseases through Matrix Metalloproteinase-13 and Sclerostin tests.

Evaluation of Matrix Metalloproteinase-13 and Sclerostin Levels in Chronic Periodontitis Patients Using Diode Laser-Assisted Scaling and Root Planing: An Experimental Study - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108535

Enrollment

Registered

2026-04-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Laser assisted scaling and root planing: scaling and root planing with and without laser in chronic periodontitis patients at baseline and after 2 months Control Intervention1: Biomarke

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patient having at least 16 functional teeth except 3rd molars will be included in the study 2 Chronic periodontitis Patients with probing pocket depth more than or equal to 5 mm and Clinical attachment level more than 3 mm 3 Patients having radiographic evidence of alveolar bone loss

Exclusion criteria

Exclusion criteria: Individuals with any type of systemic disease Pregnant or lactating patients Patients who have been taking alcohol or smoking tobacco Patients who are on antibiotic treatment or immunosuppressive medications Patients who underwent periodontal therapy in last 6 months

Design outcomes

Primary

Measure	Time frame
1 To determine MMP13 and Sclerostin levels in the GCF of Chronic periodontitis patients prior to SRP 2 To assess MMP13 and Sclerostin levels in GCF of Chronic periodontitis patients 2 month after SRP 3 To evaluate GCF MMP13 and Sclerostin levels after SRP with diode laser 4 To compare the levels of MMP13 and sclerostin after SRP and SRP with diode laser therapyTimepoint: At baseline and after 2 months	—

Measure

Time frame

1 To determine MMP13 and Sclerostin levels in the GCF of Chronic periodontitis patients prior to SRP 2 To assess MMP13 and Sclerostin levels in GCF of Chronic periodontitis patients 2 month after SRP 3 To evaluate GCF MMP13 and Sclerostin levels after SRP with diode laser 4 To compare the levels of MMP13 and sclerostin after SRP and SRP with diode laser therapyTimepoint: At baseline and after 2 months

—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactRika Singh

Institute of Dental Sciences

priyankabharatita@gmail.com09140184198

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026