Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: Propofol 2 to 3 mg/kg, fentanyl 2 micrograms/kg and atracurium 0.5mg/kg or rocuronium 0.6mg/kg, sugammadex 2mg/kg body wt
Intervention2: Nil: Nil
Control Intervention1: Neos
Sponsors
Dr Puneet Khanna
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age greater than 18 years of either sex 2. ASA physical status I-III 3. Open abdominal surgeries 4. Surgical duration greater than 1 hour 5. Patients with frailty score of greater or equal to 1 as defined by modified 5 item frailty index (5-mFI)
Exclusion criteria
Exclusion criteria: 1. H/o any neuromuscular disease 2. H/o psychiatric disease, dementia, anxiety disorder 3. Need for postoperative ICU admission 4. Patient with delirium on pre-operative assessment 5. Surgeries requiring rapid sequence intubation 6. Obese patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Residual neuromuscular block 2. Recovery of Diaphragm Function 3. Postoperative Muscle Strength 4. Time to spontaneous recovery 5. Postoperative delirium 6. Postoperative adverse eventsTimepoint: 1. Within 5 minutes 2. Within 30 minutes 3. Within 30 minutes 4. Every 15 minutes 5. 24 hours post surgery 6. Continuous monitoring in PACU | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDr Puneet Khanna
All India Institute of Medical Sciences
Outcome results
None listed