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Evaluating breathing muscle function with ultrasound to safely remove ICU patients from ventilators

A Prospective Observational Study on Ultrasound based evaluation of Diaphragmatic Excursion, Diaphragmatic Thickness Fraction and its correlation with Rapid Shallow Breathing Index for predicting weaning success in ICU patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108463
Enrollment
62
Registered
2026-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J962- Acute and chronic respiratory failure

Interventions

Intervention1: Nil: Nil

Sponsors

SRM MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are mechanically ventilated undergoing daily spontaneous breathing trials (SBTs) as part of standard weaning protocol Hemodynamically stable patients who are conscious and cooperative without sedation

Exclusion criteria

Exclusion criteria: Patients of age below 18 or above 80 years Known or suspected diaphragmatic paralysis or prior phrenic nerve Injury Chest wall deformities or abdominal conditions such as large open Wounds surgical dressing that interfere with ultrasound measurements Neuro muscular disorders such as myasthenia gravis Guillain barre Syndrome affecting respiratory muscles Severe ascites or abdominal compartment syndrome Patients who deviates from inclusion criteria

Design outcomes

Primary

MeasureTime frame
There is a significant correlation between diaphragmatic excursion diaphragmatic thickness fraction with RSBI in predicting weaning success in ICU patientsTimepoint: 2 HOURS

Secondary

MeasureTime frame
To calculate and assess the predictive value of DERSBI and DTF RSBI in determining weaning outcome To observe trends in DE,DTF and RSBI through serial ultrasound measurements during weaning periodTimepoint: 2 hour SBT until extubation

Countries

India

Contacts

Public ContactRajampeta Mohseena

SRM Institute of Science and Technology

swarnalt@srmist.edu.in8144008182

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026