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Effect of a preoperative steroid (dexamethasone) injection on pain relief after laparoscopic gallbladder surgery in adults

A randomized controlled trial evaluating the efficacy of preoperative intravenous dexamethasone in reducing postoperative pain following laparoscopic cholecystectomy - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108425
Enrollment
80
Registered
2026-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Intravenous Dexamethasone: Patients meeting inclusion underwent outpatient workup, including detailed history, physical examination, and laboratory tests. Patients will be randomized i

Sponsors

ANUSHA NICOLE PRABHU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective laparoscopic cholecystectomy (LC) for cholelithiasis. 2. Adults aged 18 to 60 years. 3. Patients classified as ASA Physical Status I or II according to the American Society of Anesthesiologists. 4. Patients able to provide written informed consent. 5. Diagnosis of cholelithiasis and cholecystitis confirmed on abdominal ultrasonography.

Exclusion criteria

Exclusion criteria: 1. Patients below 18 and above 60 years of age 2. ASA Physical Status III or IV. 3. Presence of chronic illnesses, including: Diabetes mellitus (DM), Ischemic heart disease (IHD), Chronic kidney disease (CKD), Chronic liver disease (CLD) 4. Immunocompromised states 5. Conversion of laparoscopic cholecystectomy to open surgery. 6. Patients with any intraoperative complications 7. Patients in whom drains are placed. 8. Patients in whom ERCP has been done.

Design outcomes

Primary

MeasureTime frame
Postoperative pain intensity measured using the Visual Analog Scale (VAS) score at various hours after surgeryTimepoint: Pain will be assessed using Visual Analog Scale (VAS) at 0, 6, 12, 24, 48 hours postoperatively.

Secondary

MeasureTime frame
Time to first rescue analgesia in both groups which is the time period until the patients experiences pain for the first time post operatively Timepoint: Time to first rescue analgesia in both groups will be measured & noted when the patient experiences pain for the first time post operatively

Countries

India

Contacts

Public ContactANUSHA NICOLE PRABHU

Jawaharlal Nehru Medical College, Dr. Prabhakar Kore Charitable Hospital, Belgaum

kapil.hannurkar@gmail.com9632757766

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026