Health Condition 1: C069- Malignant neoplasm of mouth, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age more than 18 yrs 2 FNAC proven cases of all T3 T4 differentiated thyroid malignancy and T1 T2 cases in which radiologically suspected node was present and neck was addressed 3 Incidentally diagnosed cases of DTC which were reoperated within 6 months of the study period
Exclusion criteria
Exclusion criteria: 1 Age less than 18 yrs 2 Previous history of head and neck malignancy excluding DTC thyroid 3 Patients with known medical thyroid diseases or benign neoplasms of the thyroid 4 Medullary and anaplastic thyroid carcinoma 5 Patients not willing to be part of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate factors predicting response to neoadjuvant chemotherapy in locally advanced oral cavity cancerTimepoint: After completion of planned neoadjuvant chemotherapy at the time of response assessment prior to surgery approximately 6 weeks from baseline depending on chemotherapy cycles | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 To correlate clinicodemographic variables with response to NACT. 2 To assess the role of tumour-related factors (tumour size depth of invasion nodal status) in predicting response 3. To analyze radiological response parameters, including tumour volume reduction & metabolic response where available 4 To correlate histopathological features with response to NACT 5 To assess the impact of response to NACT on a Resectability b Margin status c Pathological nodal burdenTimepoint: Postoperative histopathological evaluation within 4 weeks after surgery | — |
Countries
India
Contacts
Public ContactDr Aseem Mishra
mahamana madan mohan malviya cancer centre varanasi
Outcome results
None listed