Comparing the Effectiveness of Bakul Bark Extract (Used Locally vs. Orally) for Treating Severe Gum Disease

Comparative Evaluation of the Efficacy of Systemically and Locally Administered Bakul (mimusops elengi) bark Extracts as an Adjunct to Scaling and Root Planing in Generalized Moderate to Severe Chronic Periodontitis:A Randomized Double-Blind Placebo-Controlled Clinical Trial - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108383

Enrollment

Registered

2026-04-15

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 30-65 years with generalized moderate to severe chronic periodontitis. 2. Patients with at least 20 natural teeth. 3. Patients willing to give written informed consent.

Exclusion criteria

Exclusion criteria: 1. Systemically compromised patients, including those with uncontrolled systemic conditions. 2. Patients receiving ongoing antibiotic or antimicrobial therapy. 3. Smokers or users of smokeless tobacco. 4. Individuals who have received periodontal therapy in the last 6 months. 5. Pregnant or lactating women. 6. Allergy to the material.

Design outcomes

Primary

Measure	Time frame
Modified Gingival Index (MGI) by Lobene et al., 1986 (baseline, 7 days, 1 month) Papillary Bleeding Index (PBI) by Saxer and Muhlemann, 1975 Plaque Index (PI) by Silness and Loe, 1964 (baseline, 7 days, 1 month) Pocket Probing Depth (PPD) (baseline, 1 month) Clinical Attachment Loss (CAL) (baseline, 1 month) Radiographic Evaluation of Bone Level (baseline, 1 month Timepoint: Modified Gingival Index (MGI) by Lobene et al., 1986 (baseline, 7 days, 1 month) Papillary Bleeding Index (PBI) by Saxer and Muhlemann, 1975 Plaque Index (PI) by Silness and Loe, 1964 (baseline, 7 days, 1 month) Pocket Probing Depth (PPD) (baseline, 1 month) Clinical Attachment Loss (CAL) (baseline, 1 month) Radiographic Evaluation of Bone Level (baseline, 1 month	—

Measure

Time frame

Modified Gingival Index (MGI) by Lobene et al., 1986 (baseline, 7 days, 1 month) Papillary Bleeding Index (PBI) by Saxer and Muhlemann, 1975 Plaque Index (PI) by Silness and Loe, 1964 (baseline, 7 days, 1 month) Pocket Probing Depth (PPD) (baseline, 1 month) Clinical Attachment Loss (CAL) (baseline, 1 month) Radiographic Evaluation of Bone Level (baseline, 1 month Timepoint: Modified Gingival Index (MGI) by Lobene et al., 1986 (baseline, 7 days, 1 month) Papillary Bleeding Index (PBI) by Saxer and Muhlemann, 1975 Plaque Index (PI) by Silness and Loe, 1964 (baseline, 7 days, 1 month) Pocket Probing Depth (PPD) (baseline, 1 month) Clinical Attachment Loss (CAL) (baseline, 1 month) Radiographic Evaluation of Bone Level (baseline, 1 month

—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDR THENMOZHI B R

GOVERNMENT DENTAL COLLEGE AND HOSPITAL GHATI CAMPUS AURANGABAD

cddhalkari@gmail.com

Outcome results