This study aims to compare two methods of giving pain relief after gallbladder keyhole surgery to find out which method provides better pain control and reduces the need for pain medicines and helps patients recover faster

Comparing the efficacy of Ultrasound-Guided modified thoracoabdominal nerves block through perichondrial approach with oblique subcostal transversus abdominis plane block in laparoscopic cholecystectomy: A Randomized Controlled Trial - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108330

Enrollment

Registered

2026-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Ultrasound-Guided Modified Thoracoabdominal Nerves Block through Perichondrial Approach (M-TAPA): Ultrasound-guided bilateral M-TAPA block will be performed after induction of general a

M-TAPA block performed bilaterally after the induction of general anaesthesia 2.Group C

OSTAP block performed after the induction of general anaesthesia Control Intervention2: Ultrasound-Guided Oblique Subcostal Transversus Abdominis Plane (OSTAP) Block: Ultrasound-guided bilateral OSTA

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1 AND ASA II , patients undergoing laparoscopic cholecystectomy (LC) 2.18-70 yrs age 3.Able to provide informed consent for participation

Exclusion criteria

Exclusion criteria: 1.Coagulation disorders or bleeding tendency. 2.Infection at the intended block injection site. 3.Known allergy to local anesthetic agents. 4.Severe liver or kidney failure 5.Previous abdominal surgery or trauma. 6.Conversion of laparoscopic cholecystectomy to open surgery. 7.Use of analgesics or opioids within 24 hours before surgery. 8.Chronic opioid or alcohol use, or history of substance abuse. 9.Pregnancy. 10.Inability to communicate 11.Refusal to participate in the study. 12.Body mass index (BMI) more than 35kg per meter square

Design outcomes

Primary

Measure	Time frame
Total opioid (tramadol) consumption in 24 hours postoperatively.Timepoint: 0 Minutes,15 minutes,30 minutes ,1hour ,2hour ,6 hour,12 hour,24hour	—

Secondary

Measure	Time frame
NRS pain scores (at rest and movement). Time to first rescue analgesic. Sedation and PONV scores. Dermatomal sensory block range. First oral intake and mobilization times. Timepoint: 24 HOURS	—

Countries

India

Contacts

Public ContactDR SELVA A

Government Rajaji Hospital and Madurai Medical College

mbalan75@gmail.com9443135904

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026