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A study on changes in a protein amino acid present in saliva before and after dental cleaning in people with and without early gum disease.

Comparative evaluation of Salivary Taurine levels in individuals with Stage 1 Grade A periodontitis v/s Periodontally healthy individuals and its response to Non-surgical Periodontal treatment: A Clinical-Biochemical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108313
Enrollment
50
Registered
2026-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Scaling and Root planing: Stage I Grade A periodontitis to be evaluated 4 weeks after Scaling and Root Planing Control Intervention1: None: Systemically healthy patients with healthy p

Sponsors

T.P.C.Ts Terna Dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals between the age group of 18-64 years. Individuals who readily give informed consent for the study. Individuals having probing depth between 3-4mm, clinical attachment level 1-2

Exclusion criteria

Exclusion criteria: Individuals with any systemic disorders Individuals with a history of smoking Pregnant and lactating females. Individuals who have received any periodontal treatment in the previous 1 months Individuals who have received antibiotics, anti-inflammatory drugs with past 1 Months Withdrawal Criteria-If individual takes drugs after scaling and root planing , that Individual will be excluded.

Design outcomes

Primary

MeasureTime frame
1.To determine the levels of Taurine in the Saliva of Periodontally healthy Individuals. 2.To determine the levels of Taurine in the Saliva of stage 1 grade A Periodontitis Individuals. 3.To compare the levels of Taurine in the Saliva of periodontally healthy and stage 1 grade A periodontitis Individuals 4.To evaluate the levels of Taurine in stage 1 grade A periodontitis Individuals after scaling and root planing. 5.To compare the levels of Taurine in Saliva before and after scaling and root planing in stage 1 grade A Periodontitis Individuals. Timepoint: At baseline and 4 weeks after scaling and root planing—

Secondary

MeasureTime frame
To correlate clinical parameters like Plaque index (PI), Gingival index (GI), pocket depth (PD) and Clinical Attachment Level (CAL), with Salivary levels of Taurine in periodontally healthy and stage 1 grade A periodontitis individuals Timepoint: At baseline and 4 weeks after scaling and root planing—

Countries

India

Contacts

Public ContactHinan Abdul Jalil Khache

Terna Dental College And Hospital

rohitshah17@gmail.com9699860609

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026