Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: oral pregabalin tablets to pregabalin group and dexmedetomidine nebulisation to dexmedetomidine group: tab.pregabalin 150 mg, onset 60 min, duration 6- 8 hours
inj.dexmedetomidine 50mcg
Sponsors
Hindu rao hospital
Eligibility
Inclusion criteria
Inclusion criteria: weighing between 50 to 80kg ASA grade 1 and 2 undergoing elective surgies under GA
Exclusion criteria
Exclusion criteria: Patients of uncontrolled hypertension ,ischemic heart disease, AV blocks,Arrhythmias, ventricular dysfunction Patients on beta -blockers Patients with hepatic and renal dysfunction Patients of anticipated difficult airway Patient allergic to the study drug Patient unwilling to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in hemodynamic parameter like heart rateTimepoint: T0 - Baseline just before nebulisation T1 - after nebulisation prior to induction T2 - just after intubation T3 - 1 mins post intubation T4 - 3 min post intubation T5 - 10 min post intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| to compare efficacy , post op pain and sedationTimepoint: P1 - as soon as the patient arrives in recovery area P2 - at 1 hour in recovery area P3 - at 2 hour in recovery area P4 - at 6 hour in ward P5 - at 12 hour in ward | — |
Countries
India
Contacts
Public ContactKaushalya
NDMC medical college and Hindu rao hospital
Outcome results
None listed