FindTrial
Sign In

A study comparing two methods of giving propofol anesthesia( pump controlled vs manual infusion) in patients undergoing lumbar spine surgery.

A comparative evaluation on the amount of propofol used in lumbar spine surgeries using propofol based Marsh model of Target controlled infusion and manual infusion pump A randomised controlled study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108284
Enrollment
52
Registered
2026-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G544- Lumbosacral root disorders, not elsewhere classified

Interventions

Intervention1: Propofol(Target Controlled Infusion): Propofol will be administered to patients via TCI pumps based on Marsh Model. Target plasma concentration will be 3 microgram/ml. Infusion will be

Sponsors

Department of Anesthesiology and Critical Care JNMCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Physical status of ASA 1 and 2 Patients undergoing lumbar spine surgeries (laminectomy and fixation of lumbar spine)

Exclusion criteria

Exclusion criteria: 1)Physical status of ASA Class 3 or more 2)Those with significant systemic disorders 3)Those with uncontrolled hypertension and cerebrovascular disease 4)Those with comorbid diseases- liver, renal diseases, obesity (BMI more than 30 kg/square meter 5) Pregnant females

Design outcomes

Primary

MeasureTime frame
Amount of Propofol used in Lumbar spine surgeries using Marsh model of Target Controlled Infusion vs Manual Infusion PumpTimepoint: Baseline- from induction of anesthesia,intraoperative period(continuous recording of propofol consumption from induction to end of surgery), and final total dose assessed at the end of surgery—

Secondary

MeasureTime frame
1- To compare the recovery time (eye opening to verbal command) in both the groups. 2-To study the hemodynamic changes in both the groups 3- To study the adverse events in both the groups 4- To compare the amount of fentanyl administered in both the groupsTimepoint: 1- Recovery time measured from discontinuation of Propofol infusion at the end of surgery till patient opens eyes on verbal command. 2-HR & BP recorded at baseline & at 5 min interval throughout surgery 3-Adverse events recorded from induction of anesthesia upto 1 hr after extubation 4- Total fentanyl consumption (mcg) recorded from induction of anesthesia till end of surgery.—

Countries

India

Contacts

Public ContactDr Kahkashan Nehal

Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University

obaidahmad2008@gmail.com9897695761

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026