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Connection Between SHBG and Hormonal Changes in Older Indian Men above 50 years

Correlation between sex hormone binding globulin (SHBG) and andropause in indian males over 50 years: A cross-sectional study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108277
Enrollment
50
Registered
2026-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E299- Testicular dysfunction, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Abraham Paulose
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Males aged between 50 to 70 years. 2)Individuals who provide written informed consent to participate. 3)Subjects who are clinically stable and can complete the questionnaire independently. 4)Willing to undergo blood sampling for SHBG and testosterone analysis.

Exclusion criteria

Exclusion criteria: 1)Known history of primary or secondary hypogonadism (diagnosed prior to the study). 2)Current or past use (within the last 6 months) of testosterone replacement therapy, anabolic steroids, or hormonal medications that affect SHBG levels. 3)Diagnosed cases of chronic liver disease, thyroid dysfunction, renal failure, or malignancy. 4)Individuals with severe psychiatric illness or cognitive impairment interfering with reliable reporting of symptoms. 5)Subjects who have undergone orchiectomy or suffer from testicular disorders affecting hormone levels.

Design outcomes

Primary

MeasureTime frame
To determine the correlation between serum SHBG levels and the presence and severity of andropause symptoms in Indian males aged 50 90 years at single time point at recruitment.Timepoint: single time point at recruitment

Secondary

MeasureTime frame
To assess the association of SHBG with free testosterone levels, evaluate its role as a biomarker in symptomatic men with normal total testosterone, determine the prevalence of andropause, & analyze its relationship with individual symptom domains at single time point at recruitment.Timepoint: single time point at recruitment

Countries

India

Contacts

Public ContactDr K Kirubhakaran

Vinayaka Missions Kirupananda Variyar Medical College & Hospital, Salem

dr.kirubhakaranoffice@gmail.com9786876687

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026