Comparison of Sugammadex and Neostigmine on nausea and vomiting after gall bladder surgery under general anaesthesia

Effects of Sugammadex versus Neostigmine on postoperative Nausea and Vomiting after general anaesthesia in patients undergoing open cholecystectomy surgery A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108267

Enrollment

Registered

2026-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Effects of sugammadex or neostigmine on postoperative nausea and vomiting after general anaesthesia in open cholecystectomy surgery: Compare the effects of sugammadex or neostigmine on

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18-60 years of both sexes having ASA grade 1 and 2 undergoing open cholecystectomy surgery

Exclusion criteria

Exclusion criteria: Patients with known history of allergies to study the drugs used Patients with a known history of motion sickness and PONV Impaired kidney function The need for postoperative ventilation

Design outcomes

Primary

Measure	Time frame
To compare the incidence of postoperative nausea and vomiting in the first 24 hours after general anesthesia using sugammadex versus neostigmine in patients undergoing open cholecystectomyTimepoint: 0-6 hours, 6-12hours, 12-24 hours postoperatively	—

Secondary

Measure	Time frame
To compare overall recovery profile To evaluate the duration of stay in the PACU To compare heart rate, blood pressure after reversal agent administration To compare antiemetic use between the two groups in the first 24 hoursTimepoint: For first 30 minutes after extubation	—

Countries

India

Contacts

Public ContactAnupriya

Rajendra Institute Of Medical Science

mukeshgmch@gmail.com9711592269

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026