Health Condition 1: C718- Malignant neoplasm of overlappingsites of brain
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
Sri Venkateshwara Institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Histopathologically confirmed CNS gliomas (WHO Grade II - IV) (APPENDIX II). 2.Patients age 18 years and older. 3.Karnofsky performance score (KPS) more than equal to 60 (APPENDIX III). 4.Patients who are willing to give informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1.Grade I gliomas 2.Patients aged below 18 years 3.Karnofsky performance score (KPS) less than 60 4.Pregnant and lactating women 5.Non-glioma tumors of CNS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To find association between following molecular biomarkers with treatment outcomes such as one year overall survival (1 year OS). - IDH - ATRX - P53 - MGMT - 1p19qTimepoint: With MRI at 6 months and 12 months post Radiotherapy treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| To find association between the following molecular biomarkers with treatment outcomes such as progression free survival (PFS) - IDH - ATRX - P53 - MGMT - 1p19qTimepoint: With MRI at 6 months and 12 months post Radiotherapy treatment | — |
Countries
India
Contacts
Public ContactDr Pranabandhu Das
Sri Venkateswara Institute of Medical Sciences
Outcome results
None listed