A Study Comparing Two Methods of Pain Relief During Breast Cancer Surgery: Fentanyl vs. Erector Spinae Plane (ESP) Block with General Anaesthesia

A COMPARATIVE EFFICACY OF FENTANYL AND ERECTOR SPINAE PLANE BLOCK BASED GENERAL ANAESTHESIA IN ELECTIVE MODIFIED RADICAL MASTECTOMY - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108254

Enrollment

Registered

2026-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

Intervention1: Fentanyl based General anesthesia vs erector spinae block based General anesthesia: Fentanyl based General anesthesia vs erector spinae block based General anesthesia In modified radica

Eligibility

Inclusion criteria

Inclusion criteria: Female patients in the age group of 20 - 70 years Patients of ASA Grade I and II

Exclusion criteria

Exclusion criteria: Patients with BMI more than 40 kg m2 Pregnant, breastfeeding women Patients with preexisting neurological disorders or chronic pain syndromes Patients who had previous breast surgeries, radiotherapy Patients with previous surgeries to thoracic spine Patients with H/O allergy or severe adverse reactions to local anaesthetic agents were excluded

Design outcomes

Primary

Measure	Time frame
Intraoperative hemodynamic stability assessed by changes in heart rate and blood pressure pressure from baseline at predefined intervals (every 5 minutes) during surgeryTimepoint: Intraoperative hemodynamic stability assessed by changes in heart rate and blood pressure from baseline at predefined time intervals baseline (pre-induction), post-induction, post-intubation (1, 3, and 5 minutes), skin incision, and thereafter at 5-minute intervals until the end of surgery	—

Measure

Time frame

Intraoperative hemodynamic stability assessed by changes in heart rate and blood pressure pressure from baseline at predefined intervals (every 5 minutes) during surgeryTimepoint: Intraoperative hemodynamic stability assessed by changes in heart rate and blood pressure from baseline at predefined time intervals baseline (pre-induction), post-induction, post-intubation (1, 3, and 5 minutes), skin incision, and thereafter at 5-minute intervals until the end of surgery

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactSmitha Rego

Father Mullers Medical College

balakrishna.achar@gmail.com82775 42396

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026