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Evaluation of blood based systemic inflammatory index in patients with gum disease

Assessment of the aggregate index of systemic inflammation, systemic immune inflammation index and C-Reactive protein levels in patients with Chronic Periodontitis: An Observational study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/108240
Enrollment
72
Registered
2026-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Nil: Nil Intervention2: Venous blood: Venous blood will be collected by venepuncture from the antecubital vein of the left forearm under aseptic conditions with the help of 24-gauge nee

Sponsors

Dr. Sakshi Sanjay Awaghad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Within the age group of 30 to 60 years. 2. Patients having at least 20 teeth (not including third molars and teeth with orthodontic appliances, bridges, crowns, or implants). 3. At least more or equal to 2 teeth with one or more sites with probing depth of at least more or equal to 4mm . 4. At least more or equal to 2 teeth with one or more sites with interdental clinical attachment loss (CAL) more or equal to of 3-4 mm. 5. Patients who are willing to participate in the study and given their written consent.

Exclusion criteria

Exclusion criteria: 1. Patients having Systemic illnesses (i.e. cancer, human immunodeficiency syndrome, hepatic diseases, bone metabolic diseases, cardiovascular diseases, lung diseases, malignancies or disorders that compromise wound healing, radiation, or immunosuppressive therapy) 2.Chronic alcoholic patients. 3.Pregnant or lactating women. 4.History of periodontal therapy within the last 6 months. 5.Patients who are not willing to participate

Design outcomes

Primary

MeasureTime frame
)To assess Systemic Immune-Inflammation Index (SII), 2)To assess Aggregate Index of Systemic Inflammation (AISI) and 3)To assess C-reactive protein levels 4)To assess and compare Systemic Immune Inflammation Index, Aggregate Index of Systemic Inflammation and C-reactive protein levels in chronic periodontitis patients.Timepoint: NIL- one point study

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr Alka Waghmare

ACPM Dental College and Hospital, Dhule

dralkawaghmare@gmail.com9423918900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026