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A Study of Variations in Brain Blood Vessels and Their Role in Stroke Among Elderly Individuals

A study of Collateral and Morphometric Correlation of Anatomical variations in the circle of Willis and internal carotid artery in acute stroke in the elderly subjects - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108218
Enrollment
134
Registered
2026-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I668- Occlusion and stenosis of other cerebral arteries

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: nil: nil Intervention4: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Participants eligible for inclusion in this study will be individuals aged 60 years and above at the time of recruitment who are able to undergo Magnetic Resonance Imaging (MRI) with Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) and provide written informed consent, either directly or through a legally authorized representative

Exclusion criteria

Exclusion criteria: Individuals with a history of head trauma, craniotomy, or craniectomy, as well as those diagnosed with vasculitis, will be excluded, as this may affect the normal physiology of the circle of Willis

Design outcomes

Primary

MeasureTime frame
Presence of acute ischemic stroke in relation to anatomical variations of the Circle of Willis (CoW) and internal carotid artery (ICA)Timepoint: Presence of acute ischemic stroke in relation to anatomical variations of the Circle of Willis (CoW) and internal carotid artery (ICA)

Secondary

MeasureTime frame
Distribution and types of CoW and ICA variations Quantitative vessel measurements: Diameter (mm) Length (if applicable) 3.AI score for vessel dominanceTimepoint: 1.At baseline (during imaging acquisition 2.At baseline (during image analysis phase) 3At baseline (post-imaging analysis)

Countries

India

Contacts

Public ContactPurvi Mishra

Datta Meghe Medical college

kirti.kbc@gmail.com9823853840

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026