A clinical intervention to compare the effect of different root canal cleaning techniques Manual agitation, Endoactivator and CRCC. Main outcome is to know which cleaning technique is effective in reducing pain after root canal therapy in male participants with symptomatic apical periodontitis.

Comparative evaluation of the effect of manual agitation, endoactivator and CRCC irrigation techniques on post endodontic pain after single visit root canal treatment in male patients with symptomatic apical periodontitis. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108212

Enrollment

Registered

2026-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: EndoActivator: Post endodontic pain is measured in 20 male patients at 24 hours, 48 hours and 7 days after using 15/2% yellow polymer tip of EndoActivator,rate of 10,000 cycles/min with

Eligibility

Inclusion criteria

Inclusion criteria: Single rooted single canal mandibular premolar teeth in adult male patients diagnosed with symptomatic apical periodontitis. Symptomatic apical periodontitis confirmed with Periapical radiograph,EPT/ Cold test and percussion test will be included. Patients with pain ranging from moderate to severe on verbal rating scale.

Exclusion criteria

Exclusion criteria: Patients taken analgesics or anti inflammatory drugs within 12 hrs. Patients allergic to local anesthetic agents and NSAID. Patients taking opiods Asymptomatic apical periodontitis Mandibular premolar teeth with more than one root and more than one canal, calcified canals,root resorption, sinus tract, periodontal disease and mobility. Patients not willing to report during follow up periods will be excluded.

Design outcomes

Primary

Measure	Time frame
The present study will assess the effectiveness of various irrigation activation systems Manual agitation,Endoactivator and CRCC irrigation techniques on reduction of post-endodontic pain after single visit root canal treatment in patients with symptomatic apical periodontitis.Timepoint: 2 months	—

Secondary

Measure	Time frame
To provide best possible irrigation system for treatment of symptomatic patients in single visit, that will enhance the quality of practice.Timepoint: 2 months	—

Countries

India

Contacts

Public ContactDr Deepti Jain

Government dental college Raipur

drdeeptijain1980@gmail.com9425503807

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026