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Evaluation of failed root canal treatment by cone beam computed tomography and microbiological analysis

Cone-beam computed tomographic and microbiological evaluation of ineffective primary endodontic treatment :an in-vivo study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108166
Enrollment
30
Registered
2026-04-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: NIL: No therapeutic intervention. Observational study involving CBCT evaluation and microbiological/metagenomic analysis of previously treated root canal teeth. Intervention2: Nil: Nil

Sponsors

Karnavati School of Dentistry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Teeth with secondary endodontic infection and failed root canal treatment. Tenderness to percussion, Pain on palpation, Presence of sinus tract, Presence of periapical radiolucency Voids in/ around the root canal filling were recorded.

Exclusion criteria

Exclusion criteria: Teeth showing exposure of the root filling material. Teeth that have metal posts. Traumetized tooth. Patients who received antibiotic therapy in the past three months Periodontal diseases Patient not signing the informed consent.

Design outcomes

Primary

MeasureTime frame
Assessment of periapical lesions using CBCT and identification and microorganisms causing failed root canal treatmentTimepoint: 4-8 weeks

Secondary

MeasureTime frame
Microbial profile, microbial load, & its correlation with CBCT findings in failed root canal casesTimepoint: 4-8 weeks

Countries

India

Contacts

Public ContactDr Mausmee Ved

Karnavati School of Dentistry

nirajkinariwala@karnavatiuniversity.edu.in9825100249

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026