A Study to see if adding a Drug to Spinal injection improves Pain control and Anaesthesia during and after Surgery.

Comparison Of Different Doses of Dexmedetomidine as adjuvant for Infraumblical surgery in patients receiving Bupivacaine spinal anesthesia -A Three Arm Comparative study - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108112

Enrollment

Registered

2026-04-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z01- Encounter for other special examination without complaint, suspected or reported diagnosis

Interventions

Intervention1: Intrathecal Dexmedetomidine: Dose - Intrathecal dexmedetomidine 5mcg ,7.5mcg,10mcg with 0.5% Hyperbaric Bupivacaine 15mg Route-Intrathecal Frequency-Single dose given once preoperative

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and ASA 2 Elective Infra umblical surgeries under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Patient refusal Coagulopathy Allergy to local anaesthetics Severe cardiac disease Respiratory disease Hepatic and renal disease

Design outcomes

Primary

Measure	Time frame
To compare duration of postoperative analgesia among the three doses of intrathecal dexmedetomidineTimepoint: In first 15 min and 30 min then every 30 mins up to 2 hours then hourly till 6 hours	—

Secondary

Measure	Time frame
To assess onset and duration of sensory and motor block To evaluate hemodynamic stability To monitor sedation levels and adverse effectsTimepoint: In first 6 hours after surgery	—

Countries

India

Contacts

Public ContactDr Vairavarajan MD

Institute of Anaesthesiology ,Madurai medical college

drvairav@yahoo.co.in9842190336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026