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Comparing Scans and Surgery in Nose and Sinus Cancer Near the Eye

Correlation of Preoperative Imaging (CT or MRI) With Intraoperative Findings in the Management of the Orbit in Nose and Paranasal Sinus (PNS) Malignancies - ORBIT Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/108098
Enrollment
250
Registered
2026-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C300- Malignant neoplasm of nasal cavity Health Condition 2: C301- Malignant neoplasm of middle ear Health Condition 3: C319- Malignant neoplasm of accessory sinus, unspecified

Interventions

Intervention1: Nil: Nil

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosed nose or PNS malignancy (treatment-na ve or previously treated) 2. Underwent surgical treatment at the study centre (open or endoscopic) 3. Availability of preoperative CT and/or MRI imaging

Exclusion criteria

Exclusion criteria: 1. Benign sinonasal diseases 2. Inadequate or unavailable imaging for review 3. Patients operated outside the study centre

Design outcomes

Primary

MeasureTime frame
Correlation between preoperative CT/MRI imaging findings and intraoperative findings of orbital involvementTimepoint: At the time of surgery (imaging performed within 4 6 weeks prior to surgery compared with intraoperative findings)

Secondary

MeasureTime frame
1.To correlate radiological findings with histopathological confirmation of orbital or nasolacrimal invasion (when available). 2.To assess local control outcomes following treatment.Timepoint: 1. At the time of histopathological reporting (post-surgery) 2. During follow-up as per institutional schedule 3. within 30 days post-surgery/early postoperative period 4. from date of surgery to discharge 5. During the postoperative period following multidisciplinary decision-making.

Countries

India

Contacts

Public ContactDr ShivaKumar Thiagarajan

TATA MEMORIAL HOSPITAL

thiagarajans@tmc.gov.in9846572399

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026